Reducing postoperative inflammation and scarring is essential to help improve long-term patient outcomes and reduce the need for additional interventions11,12
POSTOPERATIVE CARE IMPACTS LONG-TERM OUTCOMES: improvements in quality of life after ESS at 6 months are indicative of results seen at 1.6 years.13
Elevate your postoperative care regimen beyond traditional options
In order to maintain the benefits achieved with surgery, postoperative care regimens are needed that ensure that newly opened sinuses remain open and inflammation is controlled from both the underlying disease and the procedure.4 Common postoperative regimens include4,14:
- Topical steroid sprays
- Oral steroids
- Mechanical spacers ± steroids
Although these regimens have an established role in postoperative care, they do not provide an optimal solution for all patients.
- Poor penetration into the sinus
- ~60% of active drug in a metered dose of nasal steroid spray is removed by mucociliary clearance within 15 minutes
- Only 40% patients use intranasal corticosteroids as directed
-
Oral steroids17,18
- Effective in addressing inflammation but carry systemic risks, such as
- Hyperglycemia
- Infections
- Bone loss
- Adrenal suppression
- Ophthalmic complication
- Gastrointestinal symptoms
- Psychiatric symptoms
- Obstruction impairs drainage
- Notable variability in steroid dose
- Unknown release duration of steroid
- Painful removal
- Absence of efficacy/safety data from clinical trials
Historically, there was an unmet need for postoperative care options proven in randomized controlled trials to significantly improve sinus surgery outcomes